- :Prescription Medicine
- :Silvasta 100mg 4 Tablets (only available for sale with prescription or instore consult and NZ only)
Silvasta 100mg 4 Tablets (only available for sale with prescription or instore consult and NZ only)
Prescription Only Medicine
Style number: 2381117
Note: Sildenafil has now been reclassified as pharmacist only medicine for erectile dysfunction. Net Pharmacy is now accredited to supply sildenafil without a prescription to adult males (35 to 70 years old) presenting in person after a screening process with a trained pharmacist. Our pharmacists in store are trained to consult and dispense Silvasta without a prescription from the doctor. For further details, call us on 0508 881188.
Silvasta 100mg (sidefanil citrate) is designed to treat mean suffering from erectile dysfunction. This oral therapy for the treatment of ED causes an increased blood flow to the penis. This natural stimulation of the penis leads to an erection that is sustained.
Mechanism of Action
Upon sexual stimulation, nitric oxide (NO) is released into the corpus cavernosum. NO is responsible for activating guanylate cyclise, an enzyme which induces higher levels of cyclic guanosine monophosphate (cGMP). cGMP promotes relaxation of the smooth muscles to facilitate an increased inflow of blood to the corpus cavernosum in the penis. Silvasta 100mg is a PDE5 inhibitor. Phosphodiesterase Type 5 compounds cause the breakdown of cGMP. By inhibiting PDE5, there results a higher level of cGMP in the corpus cavernosum. cGMP can relax the smooth muscles so more blood can flow into the penile tissue. What’s more, Silvasta promotes the action of NO in order to activate the NO/cGMP pathway for natural sexual stimulation. Still, there is a need for manual stimulation of the penis before Silvasta can take effect.
Silvasta 100mg has undergone randomized, double blind placebo controlled trials to test its efficacy and safety. The study consisted of over 3,000 participants between the age range of 19 to 87. Results indicate that patients experienced improved erections: over 62% for 25mg, 74% for 50mg, 82% for 100mg versus the 25% improvement for the placebo. Furthermore, the patients had improved orgasm, better intercourse satisfaction and overall satisfaction. Two other clinical studies show that sildefanil was still capable of producing an erection even after 4 to 5 hours of taking the medicine. Then, the onset of erection was within 12 to 37 minutes upon taking sildefanil.
What is Erectile Dysfunction?
Erectile Dysfunction is a condition wherein males fail to get or sustain an erection due to decreased blood flow to the penile organ. As males age, they become more susceptible to ED, more so if they have cardiovascular disease, diabetes, cancer and stroke. Certain medications and drugs can also caused ED as a side effect.
How To Treat Erection Dysfunction
One way to treat ED is to adopt a healthy lifestyle. One must exercise regularly and refrain from smoking to lower the risk of having ED. Medicines like Silvasta and PDE5 inhibitors also treat ED.